AF488 Anti-Human CD81 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20880F
Human peripheral blood lymphocytes are stained with Anti-Human CD81 Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Human CD81 Antibody
Catalog Number
RD20880F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1 (target of an antiproliferative antibody). CD81 is expressed on T and B cells, NK cells, monocytes, dendritic cells, thymocytes, endothelial cells, and fibroblasts. It also has low levels of expression on granulocytes. CD81 induces B cell adhesion via VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.
Immunogen Information
Gene ID
975
Swissprot
P60033
Synonyms
CD81 antigenCD8126 kDa cell surface protein TAPA-1Target of the antiproliferative antibody 1.Tetraspanin-28Tspan-28APA1TSPAN28
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.