AF488 Anti-Mouse CD117 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AF488 Anti-Mouse CD117 Antibody
Catalog Number
RD30222F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat
Background
CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Immunogen Information
Gene ID
16590
Swissprot
P05532
Synonyms
Mast/stem cell growth factor receptor KitKitSCFRProto-oncogene c-KitTyrosine-protein kinase KitCD117
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF488
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.