AF488 Anti-Mouse CD127/IL-7RA Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20397F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD127 Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Mouse CD127/IL-7RA Antibody
Catalog Number
RD20397F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.
Immunogen Information
Gene ID
16197
Swissprot
P16872
Synonyms
Interleukin-7 receptor subunit alphaIl7rIL-7 receptor subunit alphaIL-7R subunit alphaIL-7R-alphaIL-7RACD127
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.