AF488 Anti-Mouse CD183/CXCR3 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21400F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD183/CXCR3 Monoclonal Antibody (AF488 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Mouse CD183/CXCR3 Antibody
Catalog Number
RD21400F
Clonality
Monoclonal
Isotype
Armenian Hamster IgG
Host
Armenian Hamster
Background
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Immunogen Information
Gene ID
12766
Swissprot
O88410
Synonyms
C-X-C chemokine receptor type 3Cxcr3CXC-R3CXCR-3Interferon-inducible protein 10 receptorIP-10 receptorCD183/CXCR3
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas