AF488 Anti-Mouse CD3ε Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21245F
. Unstained splenocytes (empty black histogram) are used as control.](/upload/ec/antibodies/RD21245F-FC01.jpg)
C57BL/6 murine splenocytes are stained with Anti-Mouse CD3ε Monoclonal Antibody (AF488 Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Mouse CD3ε Antibody
Catalog Number
RD21245F
Clonality
Monoclonal
Isotype
Armenian Hamster IgG
Host
Armenian Hamster
Background
CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Immunogen Information
Gene ID
12501
Swissprot
P22646
Synonyms
T-cell surface glycoprotein CD3 epsilon chainCD3ET-cell surface antigen T3/Leu-4 epsilon chainCD3eCD3ET3E
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF488
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas