AF488 Anti-Mouse CD40 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AF488 Anti-Mouse CD40 Antibody
Catalog Number
RD20456F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Immunogen Information
Gene ID
21939
Swissprot
P27512
Synonyms
Tumor necrosis factor receptor superfamily member 5Cd40B-cell surface antigen CD40Bp50CD40L receptorCD40Tnfrsf5
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF488
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas