AF488 Anti-Mouse CD90.2 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21091F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD90.2 Monoclonal Antibody(AF488 Conjugated)(filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
Product Name
AF488 Anti-Mouse CD90.2 Antibody
Catalog Number
RD21091F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat
Background
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.
Immunogen Information
Gene ID
21838
Synonyms
Thy-1.2 membrane glycoproteinThy1.2Thy-1.2 antigenCD90.2Thy-1.2
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF488
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.