AF488 Anti-Mouse/Human CD11b Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD20954F
Mouse bone marrow cells are stained  with Anti-Mouse/Human CD11b Monoclonal Antibody(AF488 Conjugated)[Used at 0.2 μg/10<sup>6</sup> cells dilution](filled gray histogram). Unstained bone marrow cells (blank black histogram) are used as control.
Mouse bone marrow cells are stained with Anti-Mouse/Human CD11b Monoclonal Antibody(AF488 Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained bone marrow cells (blank black histogram) are used as control.
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Overview

Circle
Product Name
AF488 Anti-Mouse/Human CD11b Antibody
Catalog Number
RD20954F
Clonality
Monoclonal
Isotype
Rat IgG2b, κ
Host
Rat

Background

Circle
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Immunogen Information

Circle
Gene ID
16409 ,3684
Swissprot
P05555,P11215
Synonyms
Integrin alpha-MItgamCD11 antigen-like family member BCR-3 alpha chainLeukocyte adhesion receptor MO1CD11b

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
FCM
Conjugation
AF488
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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