AF647 Anti-Human CD11b Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21786F
Human peripheral blood monocytes are stained with Anti-Human CD11b Monoclonal Antibody(AF647 Conjuaged)(filled gray histogram). Unstained monocytes (empty black histogram) are used as control.
Product Name
AF647 Anti-Human CD11b Antibody
Catalog Number
RD21786F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Immunogen Information
Gene ID
3684
Swissprot
P11215
Synonyms
Integrin alpha-MItgamCD11 antigen-like family member BCR-3 alpha chainLeukocyte adhesion receptor MO1CD11b
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF647
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.