AF647 Anti-Human CD16 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD30456F
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Overview

Circle
Product Name
AF647 Anti-Human CD16 Antibody
Catalog Number
RD30456F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse

Background

Circle
CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Immunogen Information

Circle
Gene ID
941
Swissprot
P08637,O75015
Synonyms
FcγRIIIFc gamma receptorFc gamma receptor 3

Applications

Circle
Reactivity
Human
Tested Applications
FCM
Conjugation
AF647
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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