AF647 Anti-Human CD27 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD21737F
Human peripheral blood lymphocytes are stained with Anti-Human CD27 Monoclonal Antibody(AF647 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
AF647 Anti-Human CD27 Antibody
Catalog Number
RD21737F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.
Immunogen Information
Gene ID
939
Swissprot
P26842
Synonyms
CD27L receptorT-cell activation antigen CD27T14S152TNFRSF7
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF647
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas