AF647 Anti-Human CD32 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20902F
Product Name
AF647 Anti-Human CD32 Antibody
Catalog Number
RD20902F
Clonality
Monoclonal
Isotype
Mouse IgG2b, κ
Host
Mouse
Background
CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
Immunogen Information
Gene ID
2212
Swissprot
P31994
Synonyms
Low affinity immunoglobulin gamma Fc region receptor II-bFCGR2BIgG Fc receptor II-bCDw32Fc-gamma RII-bFc-gamma-RIIbFcRII-bCD32FCG2IGFR2
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AF647
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas