For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30737F
Human peripheral blood leucocytes are stained with AF 647 Anti-Human CD4 Antibody (Left). Leucocytes are stained with AF 647 Mouse IgG1, κ Isotype Control (Right).
CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16.