AF647 Anti-Mouse CD161/NK1.1 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20036F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD161/NK1.1 Monoclonal Antibody(AF647 Conjugated) and Anti-Mouse CD49b Monoclonal Antibody(AF488 Conjugated)(left). Splenocytes stained withAnti-Mouse CD49b Monoclonal Antibody(AF488 Conjugated)(right) are used as control.
Product Name
AF647 Anti-Mouse CD161/NK1.1 Antibody
Catalog Number
RD20036F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse
Background
NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.
Immunogen Information
Gene ID
17059
Swissprot
P27814,P27812,Q99JB4
Synonyms
Killer cell lectin-like receptor subfamily B member 1CKlrb1cCD161 antigen-like family member CLy-55cCD161/NK1.1NKR-P1.9NKR-P1CNKR-P1 40CD161c
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF647
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.