AF647 Anti-Mouse CD163 Antibody[S15049F]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30669F
C57BL/6 murine bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and AF 647 Anti-Mouse CD163 Antibody (Left). Bone marrow cells are stained with FITC Anti-Mouse/Human CD11b Antibody and AF 647 Rat IgG2a,κ Isotype Control (Right).
Product Name
AF647 Anti-Mouse CD163 Antibody[S15049F]
Catalog Number
RD30669F
Isotype
Rat IgG2a, κ
Host
Rat
Background
CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
Immunogen Information
Gene ID
93671
Synonyms
M130MM130SCARI1
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AF647
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.