C57BL/6 murine splenocytes are stained with FITC Anti-Mouse MHC II (I-A/I-E) Antibody and AF Red 780 Anti-Mouse CD11c Antibody (Left). Splenocytes are stained with FITC Anti-Mouse MHC II (I-A/I-E) Antibody and AF Red 780 Armenian Hamster IgG Isotype Control (Right).
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.
Immunogen Information
Gene ID
16411
Synonyms
Integrin alpha-XItgaxCD11 antigen-like family member CLeukocyte adhesion receptor p150+95CD11c
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AFRed 780
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.