AFRed 780 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Product Name
AFRed 780 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]
Catalog Number
RD30596F
Isotype
Rat IgM, κ
Host
Rat
Background
DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Immunogen Information
Gene ID
16398
Synonyms
Integrin alpha-2CD49 antigen-like family member BCollagen receptorPlatelet membrane glycoprotein IaGPIaVLA-2 subunit alphaCD49b
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AFRed 780
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.