AFViolet 450 Anti-Human CD62L Antibody[HI62L]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
![Human peripheral blood lymphocytes are stained with APC Anti-Human CD4 Antibody and AF Violet 450 Anti-Human CD62L Antibody[HI62L] (Left). Lymphocytes are stained with APC Anti-Human CD4 Antibody and AF Violet 450 Mouse IgG2a, κ Isotype Control (Right).](/upload/ec/antibodies/RD30725F-FC01.jpg)
Human peripheral blood lymphocytes are stained with APC Anti-Human CD4 Antibody and AF Violet 450 Anti-Human CD62L Antibody[HI62L] (Left). Lymphocytes are stained with APC Anti-Human CD4 Antibody and AF Violet 450 Mouse IgG2a, κ Isotype Control (Right).
Product Name
AFViolet 450 Anti-Human CD62L Antibody[HI62L]
Catalog Number
RD30725F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse
Background
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of na?ve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Immunogen Information
Synonyms
L-selectinSellCD62antigen-likefamilymemberLLAM-1LECAM1LymphnodehomingreceptorLy-22CD62LLnhrLy22
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AFViolet 450
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Do not freeze.