CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Immunogen Information
Gene ID
2209
Swissprot
P12314
Synonyms
Fc fragment of IgG high affinity Ia/b/c receptorCD64A/B/CCD64Fc gamma RIFCGR1A/B/CIGFR 1
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
AFViolet 450
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.