AFViolet 450 Anti-Human/Mouse KLRG-1 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
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Overview

Circle
Product Name
AFViolet 450 Anti-Human/Mouse KLRG-1 Antibody
Catalog Number
RD30508F
Clonality
Monoclonal
Isotype
Syrian Hamster IgG
Host
Syrian Hamster

Background

Circle
Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).  KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.  It is composed of a homodimer of glycosylated 30-38 kD subunits.  Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.  KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells.  KLRG1 may be involved in regulating NK cell homeostasis.  KLRG17 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

Immunogen Information

Circle
Gene ID
10219 ,50928
Swissprot
Q96E93,O88713
Synonyms
MAFA2F17-Ag

Applications

Circle
Reactivity
Human,Mouse
Tested Applications
FCM
Conjugation
AFViolet 450
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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