CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes. As a high-affinity receptor for LPS-LBP (LPS-binding protein) complex, CD14, in association with Toll-like Receptor 4 (TLR4) or 2 (TLR2), is involved in the clearance of gram-negative pathogens.
Immunogen Information
Gene ID
12475
Swissprot
P10810
Synonyms
CD 14Myeloid cell-specific leucine-rich glycoproteinMonocyte differentiation antigen CD14
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AFViolet 450
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.