Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.
Immunogen Information
Gene ID
54664417067
Swissprot
P35461,P0CW03
Synonyms
Gr-1Gr1Ly-6G/Ly-6CLy6G/Ly6C
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AFViolet 450
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.