AFViolet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody[D7]
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD30644F
C57BL/6 murine bone marrow are stained with APC Anti-Mouse CD117 Antibody and AF Violet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody (Left). Bone marrow are stained with APC Anti-Mouse CD117 Antibody and AF Violet 450 Rat IgG2a, κ Isotype Control (Right).
Product Name
AFViolet 450 Anti-Mouse Ly6A/E(Sca-1) Antibody[D7]
Catalog Number
RD30644F
Isotype
Rat IgG2a, κ
Host
Rat
Background
Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Immunogen Information
Gene ID
110454
Synonyms
Ly6aLy6Ly-6A.2/Ly-6E.1SCA-1TAP
Applications
Reactivity
Mouse
Tested Applications
FCM
Conjugation
AFViolet 450
Concentration
0.5 mg/mL
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.