The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human AGAP2
Swissprot
Q99490
Synonyms
AGAP-2Agap2Agap2 ArfGAP with GTPase domainankyrin repeat and PH domain 2AGAP2ANK repeat and PH domains 2Arf GAP with GTP binding protein likeArf GAP with GTP-binding protein-likeANK repeat and PH domains 2Arf GAP with GTP-binding protein-likeank
Gene Accession
NP_001116244
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4