This gene encodes an essential component of the N-methyl-D-aspartate (NMDA) receptor signaling complex which mediates long-term potentiation in synapses by linking activation of NMDA receptor to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking. The encoded protein contains an N-terminal GTPase-like domain, a pleckstrin homology domain, an ArfGAP domain and several C-terminal ankryn repeat domains.
Immunogen Information
Immunogen
Synthetic peptide of human AGAP3
Swissprot
Q96P47
Synonyms
AGAP-3Agap3AGAP3ANK repeat and PH domain-containing protein 3Arf GAP with GTPaseANK repeat and PH domain containing protein 3Arf-GAP with GTPaseArfGAP with GTPase domainankyrin repeat and PH domainArfGAP with GTPase domainankyrin repeat and