AIM2 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD75605A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using AIM2 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using AIM2 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using AIM2 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using AIM2 Polyclonal Antibody at dilution 1:60
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Overview

Circle
Product Name
AIM2 Polyclonal Antibody
Catalog Number
RD75605A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family. Induced by IFN-, AIM2 is thought to act as a tumor suppressor by repressing NFB transcriptional activity. Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain. The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains. The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.

Immunogen Information

Circle
Immunogen
Recombinant protein of human AIM2
Swissprot
O14862
Synonyms
Absent in melanoma 2AIM 2Aim2AIM2Interferon-inducible protein AIM2OTTHUMP00000035296PYHIN4
Gene Accession
BC010940

Applications

Circle
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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