AIMP2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70024A
Western Blot analysis of Rat liver, Rat lung tissue and Jurkat cells using AIMP2 Polyclonal Antibody at dilution of 1:600
Product Name
AIMP2 Polyclonal Antibody
Catalog Number
RD70024A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Immunogen Information
Immunogen
Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein
Swissprot
Q13155
Synonyms
Aimp2AIMP2Aminoacyl tRNA synthase complex-interacting multifunctional protein 2Aminoacyl tRNA synthetase complex interacting multifunctional protein 2ARS interacting multi functional protein 2JTV 1JTV 1 proteinJTV1JTV1 geneMultisynthase complex a
Calculated MW
35 kDa
Observed MW
35 kDa
Applications
Reactivity
Human,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas