AKAP12 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76574A
Immunohistochemistry of paraffin-embedded Human brain tissue using AKAP12 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using AKAP12 Polyclonal Antibody at dilution 1:40
Product Name
AKAP12 Polyclonal Antibody
Catalog Number
RD76574A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Synthetic peptide of human AKAP12
Swissprot
Q02952
Synonyms
A kinase (PRKA) anchor protein (gravin) 12A kinase Anchor Protein 12A kinase anchor protein 250kDaA-kinase anchor protein 12A-kinase anchor protein 250 kDaAKA12AKAP 12AKAP 250AKAP-12Akap12AKAP250DKFZp686M0430DKFZp686O0331FLJ20945FLJ97621Ger
Gene Accession
NP_005091
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas