This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9.
Immunogen Information
Immunogen
Synthetic peptide of human AKAP8
Swissprot
O43823
Synonyms
A kinase (PRKA) anchor protein 8A kinase anchor protein 8A kinase anchor protein 95A kinase anchor protein 95 kDaA kinase anchor protein 95kDaA-kinase anchor protein 8A-kinase anchor protein 95 kDaAKAP 8AKAP 95AKAP-8AKAP-95Akap8AKAP8AKAP95DK
Calculated MW
76 kDa
Gene Accession
NP_005849
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4