This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
Immunogen Information
Immunogen
Recombinant protein of human AKR1B1
Swissprot
P15121
Synonyms
ADRAKR1B 1Akr1b1Aldehyde reductase 1Aldehyde reductaseAldo keto reductase family 1member B1Aldo-keto reductase family 1 member B1aldo-keto reductase family 1member B1 (aldose reductase)Aldose reductasealdr 1ALDRaldr1ALR2ARLii5 2 CTCL tumor
Calculated MW
36 kDa
Gene Accession
BC000260
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4