AKR1C1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of Human liver cancer and breast infiltRative duct tissue, Human fetal brain tissue using AKR1C1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human colon cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human ovarian cancer using AKR1C1 Polyclonal Antibody at dilution of 1:30
Product Name
AKR1C1 Polyclonal Antibody
Catalog Number
RD76456A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Immunogen Information
Immunogen
Synthetic peptide of human AKR1C1
Swissprot
Q04828
Synonyms
2-dihydrobenzene-12-diol dehydrogenase20 alpha (3 alpha) hydroxysteroid dehydrogenase20 ALPHA HSD20 alpha hydroxysteroid dehydrogenase20-alpha-HSD20-alpha-hydroxysteroid dehydrogenase20ALPHAHSD2ALPHAHSDAK1C1AK1C1AKR1C1Aldo keto reductase famil
Calculated MW
37 kDa
Gene Accession
NP_001344
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas