ALDH8A1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75447A
Western Blot analysis of Mouse liver and kidney tissue using ALDH8A1 Polyclonal Antibody at dilution of 1:550
Immunohistochemistry of paraffin-embedded Human thyroid cancer using ALDH8A1 Polyclonal Antibody at dilution of 1:30
Immunohistochemistry of paraffin-embedded Human brain using ALDH8A1 Polyclonal Antibody at dilution of 1:30
Product Name
ALDH8A1 Polyclonal Antibody
Catalog Number
RD75447A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Three transcript variants encoding distinct protein isoforms have been identified for this gene.
Immunogen Information
Immunogen
Recombinant protein of human ALDH8A1
Swissprot
Q9H2A2
Synonyms
ALDH12DJ352A20.2
Calculated MW
53 kDa
Gene Accession
BC113862
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:25-1:100
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.