ALDOB Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD82946A
Western blot analysis of extracts of various cell lines using ALDOB Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using ALDOB Polyclonal Antibody at dilution of 1:1000.
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

Circle
Product Name
ALDOB Polyclonal Antibody
Catalog Number
RD82946A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human ALDOB (NP_000026.2).
Gene ID
229
Swissprot
P05062
Synonyms
ALDOBALDBALDO2
Calculated MW
39 kDa
Observed MW
39 kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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