This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human ALG2
Swissprot
Q9H553
Synonyms
3-mannosyltransferase ALG2ALG2 alpha-13/16-mannosyltransferaseALG2ALG2Alpha 13 mannosyltransferase ALG2Alpha-1Asparagine linked glycosylation protein 2Asparagine-linked glycosylation protein 2 homologCDGIiFLJ14511GDP Man:Man(1)GlcNAc(2) PP do
Gene Accession
BC017876
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4