ALK Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD6910R
Immunohistochemistry of paraffinembedded Human anaplastic large cell lymphoma with ALK Monoclonal Antibody(Antigen repaired by EDTA). Location: Cell membrane.
Immunohistochemistry of paraffinembedded Human anaplastic large cell lymphoma with ALK Monoclonal Antibody(Antigen repaired by EDTA). Location: Cell membrane.
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Overview

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Product Name
ALK Monoclonal Antibody
Catalog Number
RD6910R
Clonality
Monoclonal
Host
Rabbit

Background

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ALK (Anaplastic Lymphoma Kinase, cd246) is a transmembrane receptor of leucine kinase with molecular weight about 200 kDa. ALK gene was found in CD30 + anaplastic large cell lymphoma cases in 1980. If there is genetic translocation, tumor cells will produce a kind of NPM-ALK heterozygous protein (also known as p80). In normal tissues, a few cells express ALK, such as glial cells, neurons and so on. In tumor cases, literature has shown that ALK is expressed in anaplastic large cell lymphoma, inflammatory myofibroblastic tumor, rhabdomyosarcoma, leiomyoma and lung adenocarcinoma.

Immunogen Information

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Swissprot
Q9UM73

Applications

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Reactivity
Human
Tested Applications
Ready to use for IHC-P
Concentration
100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Storage Buffer
TBS with 0.1% Proclin300, PH7.4

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