This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P00709
Synonyms
a-LACTAalfaLAAlpha-lactalbuminLactalbumin alphaLactose synthase B proteinLALBALALBALysozyme-like protein 7LYZL7MGC138521MGC138523
Observed MW
16 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC-p,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-300, IF 1:100-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.