AMACR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD90704A
Western Blot analysis of Rat kidney and Rat liver using AMACR Polyclonal Antibody at dilution of 1:3000.
Western Blot analysis of Rat intestine, Mouse kidney and Mouse liver using AMACR Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Mouse kidney using AMACR Polycloanl Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Mouse kidney using AMACR Polycloanl Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human kidney using Amacr Polyclonal Antibody at dilution of 1:300
Product Name
AMACR Polyclonal Antibody
Catalog Number
RD90704A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
AMACR(Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However,AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa,suggesting a hormone-dependent expression of AMACR. It has 3 isoforms produced by alternative splicing. Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect type 4 (CBAS4).
Immunogen Information
Immunogen
Recombinant Mouse Amacr protein expressed by E.coli
Swissprot
O09174
Synonyms
2 methylacyl CoA racemase2-methylacyl-CoA racemaseAlpha methylacyl CoA racemaseAlpha-methylacyl-CoA racemaseAmacrAMACRAMACRDMacr1RACERM
Calculated MW
43 kDa
Observed MW
43 kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:1000-1:3000, IHC 1:150-1:300
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas