ANAPC15 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219631A
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ANAPC15 Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using ANAPC15 Polyclonal Antibody at dilution of 1:70(×200)
Product Name
ANAPC15 Polyclonal Antibody
Catalog Number
RD219631A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
ANAPC15 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. In the complex, it plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating to the responsiveness of the spindle assembly checkpoint. It is also required for degradation of CDC20.
Immunogen Information
Immunogen
Synthetic peptide of human ANAPC15
Swissprot
P60006
Synonyms
ANAPC15Anaphase-promoting complex subunit 15C11orf51CK051HSPC020Uncharacterized protein C11orf51
Gene Accession
NP054761
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.2 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas