ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.
Immunogen Information
Immunogen
Recombinant protein of human ANKMY2
Swissprot
Q8IV38
Synonyms
Ankmy2ANKY2Ankyrin repeat and MYND domain containing 2Ankyrin repeat and MYND domain containing protein 2Ankyrin repeat and MYND domain-containing protein 2DKFZP564O043OTTHUMP00000116019OTTHUMP00000201684ZMYND20
Gene Accession
BC035353
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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