Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Immunogen Information
Immunogen
Recombinant fusion protein of human ANKRD13A
Gene ID
88455
Swissprot
Q8IZ07
Synonyms
ANKRD13AANKRD13NY-REN-25
Calculated MW
10kDa/14kDa/17kDa/21kDa/22kDa
Observed MW
38kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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