Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.
Immunogen Information
Immunogen
Recombinant Human cytomegalovirus (HCMV) Glycoprotein B / gB Protein (His Tag)
Synonyms
Glycoprotein BgB
Applications
Reactivity
cytomegalovirus
Tested Applications
ELISA
Conjugation
Unconjugated
Dilution
ELISA 1:5000-1:10000
Concentration
1mg/mL
Storage Buffer
0.2 μm filtered solution in PBS
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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