Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described.
Immunogen Information
Immunogen
Recombinant Rat Annexin A6 protein
Swissprot
P48037
Synonyms
67 kDa calelectrinAnnexin A6Annexin VIAnnexin VI p68Annexin-6AnnexinA6AnnexinVIANX 6ANX A6ANX6ANXA 6ANXA6ANXA6Calcium binding protein p68CalelectrinCalphobindin IICalphobindin-IICalphobindinIICBP 68CBP68Chromobindin 20Chromobindin-20
Calculated MW
76 kDa
Observed MW
72 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:1000-1:4000 IHC1:100-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.