This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human AP1S3
Swissprot
Q96PC3
Synonyms
Adapter-related protein complex 1 subunit sigma-1CAdaptor protein complex AP 1 sigma 1C subunitAdaptor protein complex AP-1 subunit sigma-1CAdaptor related protein complex 1 sigma 3 subunitAP-1 complex subunit sigma-3Ap1s3AP1S3Clathrin assembly pro
Gene Accession
BC021898
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.96 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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