This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms.
Immunogen Information
Immunogen
Synthetic peptide of human AP2A1
Swissprot
O95782
Synonyms
100 kDa coated vesicle protein AAdapter-related protein complex 2 alpha-1 subunitadapter-related protein complex 2 subunit alpha-1Adaptin alpha AAdaptin alphaAdaptor protein complex AP 2 alpha 1 subunitadaptor protein complex AP 2 subunit alpha 1Ad
Calculated MW
108 kDa
Gene Accession
NP_055018
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4