APC Anti-Human CD117 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD21811F
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Overview

Circle
Product Name
APC Anti-Human CD117 Antibody
Catalog Number
RD21811F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse

Background

Circle
CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.

Immunogen Information

Circle
Gene ID
3815
Swissprot
P10721
Synonyms
Mast/stem cell growth factor receptor KitKitSCFRProto-oncogene c-KitTyrosine-protein kinase KitCD117

Applications

Circle
Reactivity
Human
Tested Applications
FCM
Conjugation
APC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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