APC Anti-Human CD20 Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20644F
Human peripheral blood lymphocytes are stained with Anti-Human CD20 Monoclonal Antibody(APC Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
APC Anti-Human CD20 Antibody
Catalog Number
RD20644F
Clonality
Monoclonal
Isotype
Mouse IgG2a, κ
Host
Mouse
Background
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
Immunogen Information
Gene ID
931
Swissprot
P11836
Synonyms
B-lymphocyte antigen CD20MS4A1B-lymphocyte surface antigen B1Bp35Leukocyte surface antigen Leu-16Membrane-spanning 4-domains subfamily A member 1MS4A1CD20
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
APC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.