APC Anti-Human CD47 Antibody[B6H12]

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Staining of normal Human peripheral blood cells with APC Anti-Human CD47 Antibody[B6H12] (filled gray histogram) or APC Mouse IgG1, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.
Staining of normal Human peripheral blood cells with APC Anti-Human CD47 Antibody[B6H12] (filled gray histogram) or APC Mouse IgG1, κ Isotype Control (empty black histogram). Cells in the lymphocytes gate were used for analysis.
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Overview

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Product Name
APC Anti-Human CD47 Antibody[B6H12]
Catalog Number
RD30864F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse

Background

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CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.

Immunogen Information

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Gene ID
961
Synonyms
Rh-associated proteingp42integrin-associated proteinIAPneurophilin

Applications

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Reactivity
Human
Tested Applications
FCM
Conjugation
APC
Concentration
5 μL/Test
Storage Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage Instructions
This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

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