APC Anti-Human CD62L Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD20704F
Human peripheral blood lymphocytes are stained with Anti-Human CD62L Monoclonal Antibody(APC Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control.
Product Name
APC Anti-Human CD62L Antibody
Catalog Number
RD20704F
Clonality
Monoclonal
Isotype
Mouse IgG1, κ
Host
Mouse
Background
CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.
Immunogen Information
Gene ID
6402
Swissprot
P14151
Synonyms
L-selectinSellCD62 antigen-like family member LLAM-1LECAM1Lymph node homing receptorLy-22CD62LLnhrLy22
Applications
Reactivity
Human
Tested Applications
FCM
Conjugation
APC
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Research Areas