APC Anti-Mouse CD127/IL-7RA Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD20401F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD127 Monoclonal Antibody(APC Conjugated)[Used at 0.2 μg/10<sup>6</sup> cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
C57BL/6 murine splenocytes are stained with Anti-Mouse CD127 Monoclonal Antibody(APC Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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Overview

Circle
Product Name
APC Anti-Mouse CD127/IL-7RA Antibody
Catalog Number
RD20401F
Clonality
Monoclonal
Isotype
Rat IgG2a, κ
Host
Rat

Background

Circle
CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

Immunogen Information

Circle
Gene ID
16197
Swissprot
P16872
Synonyms
Interleukin-7 receptor subunit alphaIl7rIL-7 receptor subunit alphaIL-7R subunit alphaIL-7R-alphaIL-7RACD127

Applications

Circle
Reactivity
Mouse
Tested Applications
FCM
Conjugation
APC
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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