APC Anti-Mouse CD183/CXCR3 Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD21404F
C57BL/6 murine splenocytes are stained with Anti-Mouse CD183/CXCR3 Monoclonal Antibody(APC Conjugated)[Used at 0.2 μg/10<sup>6</sup> cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
C57BL/6 murine splenocytes are stained with Anti-Mouse CD183/CXCR3 Monoclonal Antibody(APC Conjugated)[Used at 0.2 μg/106 cells dilution](filled gray histogram). Unstained splenocytes (empty black histogram) are used as control.
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Overview

Circle
Product Name
APC Anti-Mouse CD183/CXCR3 Antibody
Catalog Number
RD21404F
Clonality
Monoclonal
Isotype
Armenian Hamster IgG
Host
Armenian Hamster

Background

Circle
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

Immunogen Information

Circle
Gene ID
12766
Swissprot
O88410
Synonyms
C-X-C chemokine receptor type 3Cxcr3CXC-R3CXCR-3Interferon-inducible protein 10 receptorIP-10 receptorCD183/CXCR3

Applications

Circle
Reactivity
Mouse
Tested Applications
FCM
Conjugation
APC
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300, 1% BSA
Storage Instructions
Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

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